Chief & Presenting Author: Dr.Ruju Unadkat

Co Author(s): Dr.Santosh G. Honavar

Abstract

Study design: Retrospective observational case series. Purpose: Analysis of clinical presentations of CHRPE. Method: Clinical presentation, systemic associations and management were analyzed in 70 cases of CHRPE. Result: Median age was 34y. Patients were asymptomatic and disease was unilateral in 62(89%) bilateral in 8(11%). Lesions were solitary in 49(70%), grouped in 10(14%), atypical in 11(16%) cases. Most frequent location was superotemporal in 40(51%). All lesions were pigmented, flat in 70(90%), had the median largest basal diameter of 5 mm. Associated RPE adenoma was seen in 6(8%), RPE adenocarcinoma in 4(5%). 5(50%) of atypical cases had familial adenomatous polyposis. Conclusion: CHRPE is detected on routine ophthalmic evaluation in asymptomatic patients. Baseline systemic evaluation in appropriate cases and follow-up to detect morphological changes (RPE adenoma) are warranted.