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  5. FP0527 : Comparison of subfoveal choroidal thickness in preeclamptic, healthy pregnant and non-pregnant women

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Chief & Presenting Author: Dr.Aarshi Naharwal

Co Author(s): Dr.Ramanuj Samanta, Prof. Dr. Ajai Agrawal, Dr.Sreeram J

Abstract

Study design: Hospital-based comparative study.
Purpose: To compare the choroidal thickness (CT) in pre-eclamptic (PE), healthy pregnant and non-pregnant females by spectral-domain optical coherence tomography (SD-OCT) and to investigate correlation between subfoveal CT (SFCT) and mean arterial pressure (MAP) in PE.
Method: 90 females (30 in each group) were recruited. SFCT was measured bilaterally using SD-OCT(EDI) at subfoveal region and 1500 μm nasal and temporal to fovea. MAP was recorded in all.
Results: The PE group had significantly thinner choroid as compared to non-pregnant and healthy pregnant group [p<0.05] in all locations in both eyes [except for OD nasal CT] without any significant correlation between SFCT and MAP in the PE.
Conclusion: Significantly lower CT in PE without any direct correlation between SFCT and MAP may implicate that choroidal thinning in PE is governed by multifactorial choroidal vasospasm and endothelial dysfunction, instead of MAP solely.