Chief & Presenting Author: Dr. Deepak Patel

Co Author(s): Dr.Asif Shahnawaz, Dr. Nishant Kumar

Abstract

Purpose.To assess the degree of association between cataract and corticosteroid exposure in patients with asthma and COPD. Methods. A systematic literature review and meta-analysis was performed according to Systematic Reviews and Meta-analyses guidelines. The odds ratio estimates were extracted from each article. The dose-response relationship between corticosteroid exposure and the risk of cataract development was assessed.Results.A total of 17 studies met the criteria for inclusion in this review, of which 12 studies provided effect estimates for pooled analyses. All of the included observational studies reported a significant association between use of corticosteroids and cataract development in cohorts of asthma and/or COPD patients.Conclusion. ICS treatment in asthma and COPD patients is a risk factor for cataract development.