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  5. FP0705 : Comparing topical Chloroquine Phosphate,Cyclosporine A & Sodium Hyaluronate in dry eye disease.

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Chief Author: Dr.Urmil Chawla

Presenting Author: Dr.Divya Srivastava

Co Author(s): Dr.Khushboo Sheoran, Dr. Deepshikha Yadav, Dr. Jyoti Deswal

Abstract

Dry eye disease is a multifactorial disease of the ocular surface. One recent major advance in understanding dry eye disease is the recognition of role of ocular inflammation resulting in chronic nature of the disease. Purpose of the study is to compare the efficacy and safety of topical Chloroquine Phosphate 0.03%, topical Cyclosporine A 0.05% and topical Sodium Hyaluronate 0.18% in mild to moderate dry eye disease. A sample size of 105 patients ( 35 in each group ) was calculated and a prospective observational study was conducted over a period of 1 year at a tertiary care institute in Rohtak district of Haryana. Patients underwent history examination and baseline tests ( OSDI Score, Schirmer’s test, TFBUT, CFS ) to diagnose and patients with mild to moderate dry eye disease were taken up. Patients were randomly given one of the topical therapies only, and were followed at 1 week, 1 month and 3 month intervals.